Toxicity Profile for para-tert-Butylphenol (1990)
Abstract
In man, para-tert-butylphenol was a skin irritant and skin sensitizer. Occupational exposure has caused skin depigmentation. In laboratory animals, it irritated the skin, eyes, nose and mouth. para-tert-Butylphenol was of low to moderate acute oral toxicity in rats, inducing lung and liver effects. It was of low acute dermal toxicity in rabbits. Repeated oral administration caused cell proliferation in the forestomach of hamsters and rats and benign forestomach tumours in hamsters.
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