Toxicity Profile for Crocin and crocetin (1994)
Abstract
Little published information is available on the toxicity of crocin and crocetin. In poorly reported studies in rodents treated orally there were indications of toxic effects on the liver. Crocin gave negative results in bacterial tests for mutagenicity (including the Ames test) and DNA damage; it did not produce chromosome damage in mammalian cells in culture.
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