Toxicity Profile for 1,6-Hexanediol diacrylate (1990)
Abstract
1,6-Hexanediol diacrylate (HDDA) caused severe, delayed, skin irritation in humans and was reported to irritate the rabbit eye. It has given evidence of skin sensitizing potential in man and cross-reaction to other acrylates may occur. A moderate sensitizing potential has been demonstrated in guinea-pigs. HDDA demonstrated a low acute oral toxicity in rats and a low acute dermal toxicity in rabbits. Unpublished skin studies found no evidence of reproductive effects when pregnant rats were treated or of carcinogenicity in male mice. A brief citation notes that HDDA was mutagenic in mammalian cells in culture. No evidence of mutagenicity has been seen in Ames bacterial tests.
What are Toxicity Profiles?
Toxicity Profiles are comprehensive, yet concise, monographs on the hazard potential of individual chemicals.
They are written by scientists specially trained in the evaluation of toxicity data and are prepared principally from primary information sources.
View the full list of Toxicity Profiles currently available.
For further information on these expert toxicity reviews including prices, please complete the
enquiry form on the contact us page.
