Hexyl and 2-ethylbutyl acrylate (1996)
Abstract
The isomers n-hexyl (HA) and 2-ethylbutyl (EBA) acrylate were severe skin and mild eye irritants in rabbits. HA exhibited moderate to strong sensitizing potential in guinea-pigs. A small group of patients sensitized by 2-ethylhexyl acrylate cross-reacted to EBA. In acute studies, HA and EBA isomers were of low oral toxicity in rats and low dermal toxicity in rabbits. HA was not mutagenic in a bacterial Ames test. Neither isomer has been subjected to long-term studies.
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