Toxicity Profile for Tris(2-ethylhexyl) phosphite (1995)

Abstract

Tris(2-ethylhexyl) phosphite was of low acute oral toxicity in rats, mice and rabbits. Low acute toxicity was also demonstrated in rats treated by inhalation and in rabbits treated dermally. It was apparently an irritant and sensitizer in laboratory animals. The nervous system, lungs, liver, heart, spleen and blood of rats were evidently affected following repeated administration by the oral or inhalation routes. No mutagenicity was reported in an Ames test using the bacterium Salmonella typhimurium.

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