Toxicity Profile for Potassium chloride (1989)
Abstract
Potassium chloride has caused skin irritation in man and gastro-intestinal damage when administered orally. It was irritant to the eyes of rabbits. The acute oral toxicity was low in rats and moderate in mice. Feeding studies revealed gastro-intestinal effects in various species of laboratory animals but there was no evidence of carcinogenicity in rats fed potassium chloride for life. High concentrations of potassium chloride have given positive results in a range of genotoxicity screening assays using cells in culture but the results have been attributed to the changed physical environment of the cells, rather than to a direct genotoxic effect.
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