Toxicity Profile for Dicyandiamide (2000)
Abstract
Dicyandiamide did not irritate or induce sensitization when applied to the skin of volunteers. There is one report of a proven sensitization response in a worker. Acute oral and intraperitoneal toxicity was low in various species of laboratory animals. Studies involving repeated administration gave indications of effects in the liver, kidneys or blood of rats. There was no clear evidence of carcinogenic potential in rats fed dicyandiamide in the diet. Dicyandiamide was generally non-mutagenic in Ames bacterial tests.
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