Ammonia (1995)
Abstract
Ammonia is irritating to the eyes, skin and respiratory tract of man. At high atmospheric concentrations it causes serious lung injury and death. One study reported a possible skin sensitizing effect in humans, and there are a number of cases of ammonia-induced asthma. In laboratory animals a low acute inhalation toxicity is indicated. The lung was the main target of a single exposure, whilst continuous or repeated exposure over a number of weeks produced damage principally to the lung, respiratory tract, liver, kidney and heart. An increased incidence of lung infections has been noted in inhalation studies in animals. A nasal cancer has developed in a mouse exposed repeatedly to "ammonia vapour". No convincing evidence of mutagenicity was found in bacterial assays, including an Ames test.
Toxicity Profiles are comprehensive, yet concise, monographs on the hazard potential of individual chemicals. They are written by scientists specially trained in the evaluation of toxicity data and are prepared principally from primary information sources. To see the full list of nearly 500 Toxicity Profiles currently available, please click here. Profiles can be obtained by contacting our help desk (e-mail document@bibratoxadvice.co.uk) or by completing the enquiry form on the Contact Us page.
Copyright © 1995 BIBRA Information Services Ltd