Toxicity Profile for Diethylamine and its hydrochloride (1997)
Abstract
Diethylamine was severely irritant to the skin, eyes and respiratory passages of humans and various species of laboratory animals and has been reported to cause skin sensitization in humans. It was of moderate acute toxicity to laboratory animals when administered orally, dermally or by inhalation. The liver and kidneys have been identified as the main target organs in rabbits given repeated inhalation and oral exposures. No evidence of mutagenicity was seen in Ames bacterial assays. DNA damage did not occur in rats treated orally. In studies of nitrosamine formation, the combined oral administration of diethylamine hydrochloride and sodium nitrite resulted in an increased incidence of liver tumours in mice.
What are Toxicity Profiles?
Toxicity Profiles are comprehensive, yet concise, monographs on the hazard potential of individual chemicals.
They are written by scientists specially trained in the evaluation of toxicity data and are prepared principally from primary information sources.
View the full list of Toxicity Profiles currently available.
For further information on these expert toxicity reviews including prices, please complete the
enquiry form on the contact us page.
