Toxicity Profile for 2,6-Dichlorophenol (1990)
Abstract
2,6-Dichlorophenol was a severe skin and eye irritant in rabbits. It was of low acute oral toxicity in rats and mice, and caused central nervous system effects in mice. Repeated oral exposure of rats caused liver damage, decreased red blood cell levels, inhibited cell replication in the bone marrow and suppressed immune function. 2,6-Dichlorophenol caused chromosome damage in rats treated orally and there was some evidence of DNA damage in bacteria. No mutagenicity was demonstrated in mammalian cells in culture, Ames bacterial tests or yeast.
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