Toxicity Profile for 3-Methylpyridine (1990)
Abstract
3-Methylpyridine caused eye irritation, gastro-intestinal disturbances and central nervous system (CNS) effects in one worker and may have produced liver abnormalities and facial skin eruptions in another. It was a marked skin irritant in rabbits and guinea-pigs and has caused severe eye irritation in rabbits. Moderate acute oral, dermal and inhalation toxicity was demonstrated in laboratory animals, the principal site of toxic attack being the CNS. Repeated inhalation exposure resulted in increased liver weight in rats. No evidence of mutagenicity was seen in bacterial assays (including Ames tests).
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