Toxicity Profile for alpha-, beta- and gamma-Cyclodextrins (1986)

Abstract

The alpha- and beta-cyclodextrins produced kidney damage in rats and rabbits when administered by injection. They are poorly absorbed in their intact form from the gastro-intestinal tract and their oral toxicity is low. Orally administered beta-cyclodextrin gave no evidence of reproductive toxicity or genotoxicity in rats.

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