N,N'-Dimethylethyleneurea (1993)


Abstract


N,N'-Dimethylethyleneurea produced severe eye injury and moderate skin irritation in rabbits. It was of moderate acute toxicity in rats treated orally and in rabbits treated dermally. A single exposure to the saturated vapour was apparently well tolerated in rats. Tissue changes in the lungs, liver, gastro-intestinal tract and testes were observed in rats administered single oral doses or rabbits given a skin application. No studies were identified on the carcinogenicity or reproductive toxicity of N,N'-dimethylethyleneurea.


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