alpha-Phellandrene (1993)


Abstract


alpha-Phellandrene caused moderate irritation to the skin of rabbits. There was some evidence in man of skin sensitization to alpha-phelllandrene, possibly as a result of the presence of auto-oxidation products or impurities. In acute studies, alpha-phelllandrene was of low toxicity by the oral route in rats and by the dermal route in rabbits. Repeated applications to the skin of mice slightly enhanced the activity of a known skin carcinogen.


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