Toxicity Profile for Guanidine hydrochloride (1991)
Abstract
Guanidine hydrochloride was severely irritant to rabbit skin. It was of moderate acute oral toxicity in rats and had effects on the central nervous system of laboratory animals treated by the oral and subcutaneous routes. In a limited assay, chromosomal damage was not induced in mammalian cells in culture, but mutagenic activity was demonstrated in yeast.
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