Toxicity Profile for 1,2-Benzisothiazolin-3-one (1993)
Abstract
In man, l,2-benzisothiazolin-3-one (BIT) is a sensitizer causing contact dermatitis, and a skin irritant. Formulations containing BIT demonstrated a weak sensitizing potential in a guinea-pig screening test, and were skin irritants. A moderate acute toxicity was seen in rodents given BIT orally.
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