Toxicity Profile for Diethyl malonate (1996)
Abstract
Diethyl malonate was slightly irritant to the skin of rabbits and caused severe burning to rabbit eyes. No skin sensitization or skin irritation was induced in volunteers treated with dilute solutions. The ester was of low acute oral and dermal toxicity in laboratory animals. According to a brief report, no target organs were identified in rats treated orally for 90 days. Diethyl malonate was evidently not mutagenic in Ames bacterial tests.
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