Toxicity Profile for beta-Apo-8'-carotenal, ethyl beta-apo-8'-carotenoate and methyl beta-apo-8'-carotenoate (1994)
Abstract
The acute oral toxicity of these substances was low in mice. Toxic effects were not clearly demonstrated in limited studies involving repeated oral administration of beta-apo-8'-carotenal in the dog. According to brief unpublished reports of feeding studies in rats, the only toxicological effects of short-term, long-term, and multigeneration administration of beta-apo-8’-carotenal, or its methyl ester, was a reduction in testes weight. Pigment deposition occurred in various tissues, including the liver and kidney of rats and dogs. Neither beta-apo-8’ carotenal nor its methyl ester was mutagenic in an Ames bacterial test.
What are Toxicity Profiles?
Toxicity Profiles are comprehensive, yet concise, monographs on the hazard potential of individual chemicals.
They are written by scientists specially trained in the evaluation of toxicity data and are prepared principally from primary information sources.
View the full list of Toxicity Profiles currently available.
For further information on these expert toxicity reviews including prices, please complete the
enquiry form on the contact us page.
