Toxicology and Regulatory News - CONTENTS Archive

December 2005 

PART I: SHORT CUTS

Decaffeinated coffee may harm the heart
Cruciferous vegetables protect against lung cancer
Not all bad news for high-fat dairy products
Eggs – even more than they are cracked up to be
Soy consumption and risk of bone fracture
A touch of Touchi reduces blood lipids
Peanut allergy - can the severity of future reactions be predicted?
Plant food allergens – sensitization markers
Raw food diet and health
Micellar phytosterol absorption
Binge drinking and cognitive function
Dietary n-3 fatty acid and decreased dry eye syndrome
Breast milk…is that gold, silver or red top, madam?
Safety assessment of fermented milk tripeptides
An effective folic acid dose for reducing blood homocysteine levels
Are elevated homocysteine levels strongly related to heart disease?
Iron absorption and meat intake
Iron, zinc, calcium and lung cancer risk
Toenail selenium and reduced bladder cancer risk in women
Calcium, aspirin and advanced colorectal cancer
Make a beeline for propolis – a potential anti-cancer agent
Food additives and contaminants possibly linked to Crohn’s disease
Low toxicity of a promising new rice herbicide
Symptoms of pyrethrin exposure in airline flight attendants
Dichlorvos – no need for an interspecies uncertainty factor?
Neonatal exposure to PBDE (polybrominated diphenyl ethers) affects behaviour
Low level cadmium can damage kidneys
Acrylonitrile reviewed by TERA panel
Formaldehyde – chromosome damage below the UK TLV?
Carcinogenic risks of man-made vitreous fibers (MMVF) – IARC’s view questioned
Naturally occurring asbestos and mesothelioma risk
Asphalt workers, PAH exposure, and ischemic heart disease
Sericite pneumoconiosis
Diisocyanates and asthma
Diphenyl diselenide given to pregnant rats
Light thrown on retinyl palmitate’s mutagenic potential
Animal studies may predict chemicals for preventing colon cancer in humans
New assay for dermal genotoxins
Risk assessment of mixtures of thyroid hormone-disrupting chemicals

PART II: WORLD NEWS

EUROPEAN UNION

EFSA safety evaluation of flavourings
…3-(4-hydroxy-3-methoxyphenyl)propanal
…3-(4-methoxyphenyl)propan-1-ol
…3-phenylpropyl butyrate
…3-phenylpropyl benzoate
…3-phenylpropyl 3-phenylpropionate
…4-hydroxy-3,5-dimethoxycinnamic acid
…4-hydroxy-3-methoxycinnamic acid
…pentyl cinnamate
Chia seeds doubt for EFSA
Lower protein infant formula receives favourable EFSA opinion
EFSA considers whether foodstuffs containing fructose should be labelled
Ten more food-contact assessments from EFSA
…tri-n-butyl acetyl citrate
…poly(6-morpholino-1,3,5-triazine-2,4-diyl)-(2,2,6,6-tetramethyl-4-piperidyl)imino)hexa-…methylene-(2,2,6,6-tetramethyl-4-piperidyl)imino)
…1,3-dioxolane
…5-sulphoisophthalic acid, monolithium salt
…1,3,5-trioxane
…3-aminopropyltriethoxysilane
…1,2-bis(triethoxysilyl)ethane
…1-isocyanato-3-isocyanatomethyl-3,5,5-trimethylcyclohexane homopolymer, methyl ethyl ketone oxime-blocked
…2,4-bis(2,4-dimethylphenyl)-6-(2-hydroxy-4-n-octyloxyphenyl)-1,3,5-triazine
tricyclodecane dimethanol-bis(hexahydrophthalate)
EFSA opinion on Epoxy Phenolic Novolac Resins
Summaries of EU and national legislation on food contact materials
EU risk assessment reports on piperazine and zinc oxide
Publications on herbal medicinal products issued by EMEA (linseed, psyllium seed, ispaghula seed, ispaghula husk and valerian root)
EMEA draft guideline on non-clinical testing of paediatric medicines
EFSA: harmonised approach for the risk assessment of genotoxins and carcinogens

UNITED KINGDOM

COT deliberations
...quinoline yellow (E104)
...sunset yellow (E110)
...carmoisine (E122)
...ponceau 4R (E124)
...indigo carmine (E132)
...brilliant blue (E133)
...sodium benzoate (E211)
...sulphur dioxide (E220)
...monosodium glutamate (E621)
...acesulfame K (E950)
...aspartame (E951)
...saccharin (E954)
...uranium
...perfluorooctanoic acid (PFOA) and perfluorooctane sulfonate (PFOS)
Provisional pesticide approvals for fluopicolide and prosulfocarb
DEFRA plans action on PFOS (perfluorooctane sulphonate)

UNITED STATES

FDA considers qualified health claims for tomato (and products) and lycopene
Disappointing news on soy from AHRQ
EPA pesticide risk assessments
...chloroneb
...dimethipin
...endothall
...ethofumesate
...tau-fluvalinate
...thidiazuron
...MCPB
...dicloran
...propylene oxide
...oxydemeton-methyl
CERHR draft expert panel report for DEHP (di(2-ethylhexyl) phthalate)
Child specific reference doses proposed by OEHHA
Cosmetic Ingredient Review (urea, gum Arabic, mink oil)
Alternative methods assessed by NICEATM/ICCVAM for testing effects of chemicals on eyes

OTHER AUTHORITATIVE BODIES

WHO – petroleum products in drinking water
NEG criteria document for ammonia
NICNAS reports on tris(2,3-dibromopropyl)phosphate and on a formaldehyde polymer
CICAD news on tin, alkyl tins, resorcinol, cobalt, alkoxyethanols, tetrachloroethene and iodine

PART III: LEGISLATION

EUROPEAN UNION

Foods for particular nutritional uses – draft Commission Directive
EC Regulation on nitrate levels in vegetables
Maximum residue levels for pesticides given in new Commission Directive
Plant protection products get the OK
Commission Decision requires withdrawal of naled from plant protection products
Feed additive authorisations given in new Commission Regulations
EC community register of feed additives
Genetically modified maize products

UNITED STATES

Cheesy FDA approval for vitamin D3
GRAS status letters issued by FDA
EPA pesticide tolerances and exemptions