Toxicology and Regulatory News - CONTENTS Archive

Volume 45, Number 1

January 2006 


PART I: SHORT CUTS

Aspartame carcinogenicity - rather sour news
Nitrates and nitrites mutagenic in fruit flies
Coffee may protect against DNA damage…
…but high coffee consumption may be a factor in late foetal death
Healthy maternal diet helps maintain pregnancy
Lung cancer risk, meat and vitamin C supplementation
3-Hydroxy-3-methyl butyrate (HMB) tested in a 90-day study
DDE (dichlorodiphenyldichloroethylene) prenatal exposure and development of asthma
Going back to Vietnam and TCDD
Reference levels for respirable crystalline silica
...and formaldehyde
Chromium (VI) compounds and cancer
Occupation and leukaemia
MSDS and benzene
Drilling hurts the dentist too! - mercury
Neurotoxicity of dimethylamine borane after dermal exposure
Contact allergy to diazolidinyl urea (DU) - threshold considerations faced
Predicting potency of human skin sensitizers

PART II: WORLD NEWS

EUROPEAN UNION

Aspartame carcinogenicity – initial EFSA response to rat study
EFSA safety evaluation of flavourings
Lycopene from Blakeslea trispora - EFSA evaluation
Limited EFSA verdict on ITX (2-isopropyl thioxanthone) in food contact materials
EFSA urges further reductions of non dioxin-like PCBs in food and feed
Feed additive assessment by EFSA - Croxidin®
Good news from EFSA on declining human exposure to banned pesticides
REACHing ever onwards
ECETOC publications
…vinylidene floride
…biomonitoring
EU environmental risk assessment report on MCCP (medium-chain chlorinated paraffins)
SCHER view on non-animal tests for endocrine-disrupting chemicals

UNITED KINGDOM

ACNFP opinion on clinoptilolite…
….and phytosterols
SACN publish draft report on folate
Children on the FSA menu
COT December deliberations
…marine biotoxins
…uranium
…tryptophan
…kava kava
…brominated dioxin-like compounds (PBDDs, PBDFs, PBBs)
ACP evaluation of 2-(thiocyanomethylthio) benzothiazole (TCMBT)
COM statement on the biomonitoring of genotoxicity in pesticide applicators
Vinyl chloride considered by IIAC
Proposed workplace exposure limit (WEL) for respirable crystalline silica
HSC proposal for revised asbestos legislation
COC discussions include alcohol and traffic exhaust

UNITED STATES

NTP provides bitter sweet news on aspartame
Pesticide petitions filed with the EPA
EPA risk assessments on pesticides
NCEA draft air quality criteria documents for lead and nitrogen oxides
EPA EDOCKET system replaced by FDMS

OTHER AUTHORATIVE BODIES

Dutch OELs
State of the Science Reports for Screening Health Assessments
NICNAS report on potassium perfluorobutane sulfonate
SIDS Initial Assessment Reports
…diallyl phthalate
…2,4,6-tribromophenol
…ethylene glycol phenyl ether
…iron dichloride
…ε-caprolactone
…1-chloro-1,2,2,2-tetrafluoroethane
…1,1,1,2,2-pentafluoroethane
…high boiling ethylene glycol ethers (triethylene glycol butyl ether; tetraethylene glycol methyl ether; tetraethylene glycol butyl ether)
RIVM reports

PART III: LEGISLATION

EUROPEAN UNION

Food contact materials
…BADGE (bisphenol-A diglycidyl ether)
…NOGE (novolac glycidyl ethers)
…BFDGE (bisphenol-F-diglycidyl ether)
Undesirable substances in animal feed
Flugestone acetate residues in foodstuffs of animal origin
Restrictions in the use of toluene and trichlorobenzene
Perfluorooctane sulfonates carpeted

UNITED KINGDOM

Contaminants in food
Plant protection products – regulations amended

UNITED STATES

FDA approval for n-octanol from 1,3-butadiene
EPA pesticide tolerance for tralkoxydim