Toxicology and Regulatory News - CONTENTS Archive

November 2005 

PART I: SHORT CUTS

Good news for cheese lovers
Well-cooked meat and pancreatic cancer
Sugary drinks and cancer of the pancreas in women
Green tea and stomach cancer
Fruit and vegetables do not prevent ovarian cancer
Bladder cancer risk unaffected by healthy eating
Glycemic load and breast cancer
An olive oil dressing isn’t necessarily beneficial
Argan oil may help the heart
Linoleic and linolenic acid reduce pneumonia risk
Dietary fatty acids and Parkinson’s disease
Lycopene and tomato products – conference report
Effect of fruit and vegetable antioxidants on stomach cancer
Cancer risk associated with smoking and β-carotene supplementation
Homocysteine, folate and cognitive function
Selenium intake and prostate cancer
Childhood leukaemia and pesticides
Beryllium – occupational health standards inadequate?
Titanium dioxide – breathe a sigh of relief?
Painting and bladder cancer
Organic solvents and Non-Hodgkin’s lymphoma
Rare skin cancer associated with aromatic and/or halogenated hydrocarbons
Breast cancer in the US Army related to VOCs
Textiles and colorectal cancer
1,4-Dichloro-2-nitrobenzene – 90-day study
Fluorotelomer alcohol
Do animal studies overestimate the health risks from dioxins?
Diethanolamine may not be a human liver carcinogen
Mechanistic investigation of triethanolamine carcinogenicity
Adipic polyester skin allergy
Another reason to avoid being kissed by auntie - contact allergy to octocrylene
Intravenous propylene glycol – bad news for sick patients
Skin sensitisers – (Q)SARs and chemical reaction mechanisms
Biological significance of DNA adducts
High throughput bacterial mutagenicity assay

PART II: WORLD NEWS

EUROPEAN UNION

EFSA risk assessment on genetically modified (GM) oilseed rape
Food contact materials
EFSA opinion on di(2-ethylhexyl) adipate (DEHA) migration into fatty foods
CVMP guidelines on maximum residue limits for veterinary medicinal products
ILSI monograph on threshold of toxicological concern ( TTC )
ECETOC JACC review on hexafluoropropylene
SCHER verdicts on risk assessments (tetrabromobisphenol A; nitrobenzene)
SCENIHR deliberation on the health risk of nanoparticles
SCCP deliberations……
……on the cancer risk from use of hair dyes
……on the safety of two hair dye ingredients (2,6-dimethoxy-3,5-pyridinediamine dihydrochloride; 4-amino-m-cresol)
……on fluoride in toothpaste
……on microfine zinc oxide
……and on climbazole
When is a cosmetic product really a medicine?
SCCP spells out the key issues for skin sensitisation studies
Immunotoxicity testing guidelines issued by EMEA

UNITED KINGDOM

Salt intake reviewed by the MRC
Nitrate in lettuce and spinach monitored by FSA
FSA estimate 3-monochloropropane-1,2-diol in UK diet
COT seeks advice from its sister committees, the COC and COM, on furan
COM discuss pesticide applicators and scan the horizon
Nanomaterials reviewed by COT, COC and COM
COM and COC consider target organ mutagenicity data in carcinogen risk assessment
Vacancies at the COC and COM

UNITED STATES

FDA considers qualified health claims for calcium supplements
EPA pesticide risk assessments
ATSDR draft Toxicological Profiles (acrolein; arsenic; barium and its compounds; benzene; heptachlor/heptachlor epoxide; lead; xylenes; perchlorates)
IRIS review of toluene
Environmental tobacco smoke considered by OEHHA
PM2.5 and mortality assessed by OEHHA
NCEA lead model for exposure assessments

OTHER AUTHORITATIVE BODIES

UN list of banned chemicals

PART III: LEGISLATION

EUROPEAN UNION

Maximum residue levels for pesticides
Plant protection products get the OK (MCPA; MCPB; bifenazate; milbemectin)

UNITED KINGDOM

Tryptophan regulations
CHIP – Approved Supply List
Volatile organic compounds in paint, varnishes and vehicle refinishing products
Restrictions on the use of hazardous substances in electrical/electronic equipment

UNITED STATES

GRAS status of tomato pulp powder
FDA food labelling for sodium
FDA Food Code 2005
EPA pesticide tolerances and exemptions (amicarbazone; fenpropathrin; kasugamycin; pyriproxyfen; pyridaben; imidacloprid)