Toxicology and Regulatory News - CONTENTS Archive

September 2005 

PART I: SHORT CUTS

FEMA GRAS criteria and re-affirmation
Coffee is a quick worker
Soybean protein may help to lower blood pressure
Cod liver oil and birth weight
Food matrix affects allergen action
Bad news for crudités
Protective effect of carotenoids against colorectal adenoma development
Prostate cancer prevention
Multivitamins and prostate cancer
Lutein and premature birth
Genotype, vitamin D and breast cancer
Irradiated mushrooms can help bone health
Diet and skin cancer
Lose weight on the Koala diet
A long-term view of conjugated linoleic acid
Mode of action of ochratoxin A-induced kidney tumours
Pesticide exposure linked to leukaemia and lymphoma incidence
The lighter side of thiabendazole’s genotoxicity
Questions raised about formaldehyde exposure and nasopharyngeal cancer
PAHs and cancer of the larynx
Cement and cancer of the esophagus
Occupational exposure to various chemicals and prostate cancer
Hydrogen sulfide - don’t hold your breath
Ethylene glycol ethers may increase the menstrual cycle length
Man might generate higher levels of toxic DEHP metabolites
Effects of low-level exposure to o-dichlorobenzene
Chloramine sensitisation
Cleaners – cut down on the bleach!
Genotoxicity of nicotine
Impact of the EU Nickel Directive
Endocrine activity of parabens
Hair dyes and childhood cancer
Contact dermatitis to sodium stearoyl lactylate
MDI and patch-test results
Human health risk assessment of pharmaceuticals in the environment

PART II: WORLD NEWS

EUROPEAN UNION

EU food-contact assessments
EFSA guidance to assess animal feed additives
EFSA risk assessments of tolclofos-methyl and triticonazole
Pirimicarb doesn’t ruffle feathers
EU risk assessment reports on musk xylene, but-2-yne-1,4-diol and anthracene
SCCP reviews risk of sensitisation to 2-mercaptobenzothiazole ( MBT )
Classified cosmetic ingredients…an SCCP view
SCCP verdict on glyoxal, a category 3 mutagen
Colourful SCCP opinions on CI Solvent Red 23, Acid Green 25 and Acid Blue 62
SCCP approvals for benzoic acid and sodium benzoate
Phototoxic effects of extracts and oils from Tagetes spp.
Triclocarban in antibacterial soaps and shower gels
ECVAM current status of alternative test methods for cosmetics
ECVAM guidance on Good Cell Culture Practice (GCCP)

UNITED KINGDOM

FSA proposed salt targets
Children’s menu considered by FSA
VPC hormonal substances in food-producing animals

UNITED STATES

EPA pesticide tolerances
EPA risk assessments on pesticides
CERHR draft expert panel report for DEHP
EPA Integrated Risk Information System (IRIS) – recent additions
IRIS review of zinc and compounds
OEHHA listing of nitapyrin and perchlorate
Latest CIR opinions and reviews
NCEA application of PBPK models
NICEATM alternative methods

OTHER AUTHORITATIVE BODIES

Dietary phytosterols assessed by RIVM
GM foods – WHO safety and risk assessment
JECFA veterinary drug residues
CICADs on butyl acetates, inorganic tin compounds and brominated phenols
Swedish consensus reports
DECOS occupational exposure limit for bitumen
RIVM screens chemicals for reproductive toxicity
IPCS cancer mode of action and risk assessment
OECD review - thyroid hormone disruption assays

PART III : LEGISLATION

EUROPEAN UNION

Genetically modified maize
Betaine
Feed additive authorisations
Organic production of agricultural products
Veterinary medicinal products in foodstuffs of animal origin

UNITED KINGDOM

Food Supplements Act
Food labelling amendments
Draft legislation on food contaminants
Cosmetics regulations corrected and extended
Nickel regulations

OTHER AUTHORITATIVE BODIES

Switzerland - Classification, packaging and labelling of dangerous substances