Toxicology and Regulatory News - Contents Archive

Volume 47, Number 5

May 2008

PART I: WORLD NEWS

INTERNATIONAL

IARC verdicts on aromatic amines, organic dyes and related exposures
Revised OECD Test Guidelines on repeated dose inhalation toxicity
Report of the 68th JECFA meeting

EUROPEAN UNION

REACH up a gear for pre-registration
… download the IUCLID 5 pre-registration plug-in
… and settle down to some more bedtime reading
SCHER evaluates risk assessment reports
Biocide evaluations available from EC Environment
EFSA assesses the safety of mercury in animal feeds
Provisional EC list of additives for food-contact plastics
List of European and national legislation on food-contact materials
Savouring flavourings – more EFSA evaluations
Colourful EFSA assessment for lycopene in food
EFSA statement on 3-monochloropropane-1,2-diol (3-MCPD) esters
ECETOC report on the extended one-generation reproductive toxicity study

UNITED KINGDOM

COC discusses 1,3-butadiene and Non-Hodgkin’s lymphoma (NHL)
Terephthalic acid – COT draft update statement
COT review of organophosphorus compounds
HSE report on pesticide-related illness
Chlorinated drinking water and cancer – COC waiting for the last drop!
Water chlorination and adverse pregnancy outcome – draft COT statement
COC discusses mixed up carcinogens
COT looks at air fresheners
Bracken considered by COT
Pyrrolizidine alkaloids (PAs) in food – second draft COT statement
FSA Board considers study on food additives and hyperactivity in children
COT discusses FSA-funded studies on food additive mixtures and caffeine
ACNFP April deliberations
COC considers OECD Guidance Document for carcinogenicity studies
… as well as IPCS mode of action (MOA) and human relevance
All change at the HSE

UNITED STATES

More NTP nominations
Company submissions to the EPA HPV Program and EPA’s commitments under ChAMP
No significant risk level (NSRL) set by OEHHA for C.I. Direct Blue 218 and ethylbenzene
National Ambient Air Quality Standards (NAAQS) for ozone issued by EPA
Pesticide tolerance petitions filed with the EPA
EPA pesticide tolerances and health risk assessments
Risk assessments issued by EPA as part of its pesticide reregistration programme
EPA Registration Reviews for eight pesticide ingredients
FDA GRAS status for krill-derived lecithin

OTHER AUTHORITATIVE BODIES

NICNAS – Full Public Reports on new chemicals
DECOS reviews on the carcinogenicity and genotoxicity of various chemicals
Skin penetration data for substances on the Swedish OEL list
RIVM evaluates strategies for reproductive toxicity testing

 

PART II: SHORT CUTS

Testing time for 8-2 fluorotelomer alcohol in rat study
Multi-wall carbon nanotubes (MWCNTs) show genotoxic potential in rats
Chlorpyrifos and male reproductive health
Endocrine disruptors reviewed
Severe allergic response to salicylamide
Di-2-ethylhexyl terephthalate not carcinogenic in rat study
Reproductive toxicity of tetrahydrofurfuryl alcohol (THFA) in rats
Butter flavouring and lung disease – cases may spread beyond popcorn workers
Rat feeding study suggests no elegies for ellagic acid
Safety assessment of modified gum acacia
Weighing up safety of whey growth factor extract
Lung cancer risk and vitamin supplements
White tea and colon cancer
Three generations of rats raised on genetically modified (GM) corn