PART I: WORLD NEWSINTERNATIONALIARC verdicts on painting and fire-fighting More Poisons Information Monographs (PIMs) from IPCS OECD issues draft guidance for single-dose study (to derive acute reference dose) … … while existing OECD guidelines achieve celebrity status
EUROPESCCP deliberations … on toluene-2,5-diamine … on 2-hydroxyethylamino-5-nitroanisole … on 3-methylamino-4-nitrophenoxyethanol, HC Blue No. 11 and HC Violet No. 2 … and on polidocanol Biocide evaluations available from EC Environment Six more pesticide draft assessment reports released by EFSA EFSA assesses animal feed contamination by chlordane LLRICE62 – genetically modified rice approved by EFSA UNITED KINGDOMCOM Statement on the mutagenicity of terephthalic acid – new studies considered Threshold approach to formaldehyde mutagenicity – COM Statement released Cancer risks from low-level asbestos exposure – WATCH this space A dusty WATCHing brief ACNFP November deliberations Mutagenicity of sodium benzoate and potassium sorbate considered by COM Caffeine consumption during pregnancy – COT re-evaluates data COT to assess the not-so-sweet taste of honey with pyrrolizidine alkaloids UNITED STATESIRIS draft toxicological review for 1,2,3-trichloropropane issued by EPA NTP studies in GM mice – benzene and dicyclohexylcarbodiimide Ethylbenzene – OEHHA unit risk factor and cancer potency values EPA High Production Volume (HPV) chemical hazard characterizations OEHHA derives NSRL for nitromethane Pesticide tolerance petitions filed with the EPA for quaternary ammonium compounds Pesticide tolerances issued by the EPA for acetamiprid and ethalfluralin RED progress announced by EPA OEHHA proposes child-specific health criteria for chlorpyrifos NTP CERHR issues Expert Panel report on bisphenol A FDA extends the food additive use of cetylpyridinium chloride in poultry FDA GRAS status – no hang-ups for suspended lutein Alternative methods recommended by ICCVAM for testing chemicals on eyes OTHER AUTHORITATIVE BODIESDECOS considers HBROEL for platinum and compounds NICNAS – Full Public Reports on new chemicals Should ethylene glycol be considered “toxic” under CEPA? RIVM staff evaluate nanoparticle movements in the body BfR recommends a specific migration guidance value for di-isobutyl phthalate RIVM proposals for a respiratory alternative to the LLNA PART II: SHORT CUTSDevelopmental neurotoxicity of dimethyltin in rats Solvents and end stage renal disease (ESRD) Multiwalled carbon nanotubes (MWCNTs) and immune function Genotoxic blues for human cells exposed to CI Disperse Blue 291 Quaternary ammonium compounds (QACs) put through their genotoxicity paces Unsuccessful attempt to scale perfluoroalkane acids for risk assessment Adults can also display leaden responses (and some of us do) Statistics, mercury and autism Uranium mimics oestrogen in mice Cancer in hormone-sensitive tissues and acrylamide – are they linked? Overweight? Blame it on bisphenol A Developmental toxicity of tebuconazole and epoxiconazole Reproductive toxicity seen in male mice given zearalenone Seasonal cheer for Touchi in short-term rat study and genotoxicity assays Magnolia bark passes muster in safety evaluation studies Protein glutaminase assessed in 90-day rat study and genotoxicity tests Salba grain (from Salvia hispanica) may reduce cardiovascular risk in diabetics Genistein may advance prostate cancer development Safety evaluation of a DHA-rich algal oil Bright news on the sunshine vitamin Harmonisation of skin notation used with occupational exposure limits |