TOXICITY PROFILESUpdated BIBRA Toxicity Profile on palladium and its compounds PART I: WORLD NEWSINTERNATIONALWHO reviews risks of nickel in drinking water Report of the JECFA 65th meeting IPCS – skin sensitization risk assessment EUROPEAN UNION
Guidance on REACH – naming chemicals, and evaluating dossiers and substances Environmental RARs on four ethylene glycol and propylene glycol ethers SCCP deliberations on ... … methyl-N-methylanthranilate … benzophenone-3 … camphor benzalkonium methosulfate … 2-phenylbenzimidazole-5-sulfonic acid and its salts … diethylene glycol monoethyl ether … and diethylene glycol monobutyl ether SCCP guidance for the testing of cosmetic ingredients EFSA evaluation of a feed additive containing organic selenium Low-dose effects of bisphenol A disregarded by EFSA EFSA assesses safety-in-use of formaldehyde in gelling agents used in food Polyethylene glycols as coatings for food supplements assessed by EFSA EFSA evaluates 1,2-benzisothiazolin-3-one as an impurity in saccharin EFSA guidance on uncertainties in dietary exposure assessment UNITED KINGDOMHSE REACH out to the COT Compendium of chemical hazards issued by Health Protection Agency Nanomaterial toxicity – COT to consider amending joint Statement COM February deliberations IGHRC guidelines on route-to-route extrapolation in risk assessment UNITED STATES
NTP studies on 4-methylimidazole Submissions and updates to the EPA HPV Program Proposed child-specific health criteria for lead – final OEHHA draft OEHHA evaluates health effects of recycled tyres in playgrounds Pesticide tolerance petitions filed with the EPA EPA pesticide tolerances for spiromesifen and thiabendazole EPA Reregistration Eligibility Decisions FDA GRAS status letters OTHER AUTHORITATIVE BODIES
Swedish consensus reports Revealed: the vinyl chloride industry’s murky past RIVM fact sheets on ... … changes in blood biochemistry and liver damage ... quantitative risk assessment using the LLNA ... and relevance of increased Leydig cell tumours PART II: SHORT CUTS
Acrylamide and cancer in man – the evidence weakens Formaldehyde – a human carcinogen? Ethylbenzene shows no developmental toxicity in a rat study Xylenes may enhance ethylbenzene-induced ear effects Silica and lung cancer – confounding factors Indium oxide may cause lung damage in workers Tolerable daily intake for sodium monofluoroacetate – possums beware! Pesticides further incriminated in the etiology of Parkinson's disease Contact sensitivity to the UV filters octyl salicylate and Tinosorb M™? Allergic contact dermatitis: Laureth 12 and idebenone Possible estrogenic activity of lavender oil and tea-tree oil in prepubertal boys Anaphylactic reaction to acid citrate dextrose? Carcinogenicity of dibromoacetic acid Bisphenol antioxidants and male reproductive toxicity Furan study demonstrates no genotoxicity in human cells and mice FEMA GRAS re-affirmation of aromatic substituted secondary alcohols, ketones and related esters Safety and bioavailablity of ubiquinol for oral use in humans Meta-analysis finds no clear link between folate and breast cancer Maternal folic acid supplements and the risk of facial clefts Folate fortification and vitamin B12 deficiency – good and bad news for the elderly Vitamins B6 and B12, folic acid supplementation and cognitive function Vitamins, carotenoids and the risk of precancerous lesions in the mouth Vitamin supplement combination fails to protect against stomach cancer Methionine, vitamin B6 and pancreatic cancer Diet and the risk of venous thromboembolism (VTE) Children may breathe a little more easily with long-chain polyunsaturated fatty acids Supplemental calcium and the risk of colorectal adenoma recurrence Hearty effects of plant sterols Olives as a cause of contact dermatitis? Onion and colon cancer Three coffees a day may keep dementia away A healthier heart for moderate drinkers? Dietary oils may affect immune function Fishy analysis of risks and benefits Genotoxicity testing – IWGT interpretation and strategies
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