TOXICITY PROFILESUpdated bibra Toxicity Profile on sodium stearate PART I: WORLD NEWSINTERNATIONALIARC verdicts on alcoholic beverages and ethyl carbamate (urethane) WHO drinking water guidelines on dicofol, methoprene, novaluron, pirimiphos-methyl and pyriproxyfen EUROPEAN UNIONEFSA establishes acute reference dose for imazalil Genetically modified maize assessed by EFSA UNITED KINGDOMCOC Statement on prostate cancer and pesticide exposure – causal link not established Ice structuring protein – ACNFP draft opinion UNITED STATESIRIS draft toxicological review issued by EPA for nitrobenzene NTP technical reports – two final and several draft reports available More NTP nominations Submissions to the EPA HPV Program CIR final reports on capsicum-derived ingredients, phytantriol and polyethylene Pesticide tolerance petitions filed with the EPA EPA pesticide tolerances and exemptions FDA considers qualified health claim for corn oil and reduced risk of heart disease OTHER AUTHORITATIVE BODIESRIVM verdict on chemical categories and read-across in the context of REACH PART II: SHORT CUTSDiethyl phthalate and Clophen A60 may act synergistically across the generation gap DNA adducts in workers exposed to low concentrations of ethylene oxide (EO) Mercury emissions from power plants and IQ Prenatal manganese and childhood behaviour – secrets of the tooth fairy Nickel skin allergy – sensitization dose fundamentals explored Allergic contact dermatitis to polyethylene glycol-7 hydrogenated castor oil Occupational contact allergy to cysteamine hydrochloride in perms Increasing incidence of sensitization to the hair dye ingredient para phenylenediamine… … are the dermatologists partly to blame? Dermally applied trans-capsaicin tested for carcinogenicity in mice Arsenic in a kelp supplement An updated assessment on tartrazine Genotoxicity of stevioside – not such sweet news Vitamin D in pregnancy and childhood wheezing Antioxidants and teeth Re-examination of rat kidney cancers found in NTP quercetin study Flavonoids and the risk of cardiovascular disease mortality Apple polyphenols and cholesterol oxidation products Lignans may help prevent colorectal cancer … and breast cancer Babies see better with pre-natal docosahexaenoic acid? Bone health and n-3 fatty acids Docosahexaenoic acid for lower blood pressure? Almonds may stop blood glucose going nuts Lipid transfer protein (LTP) confers cross-reactivity to rice, apple and peach Hearty coffee effects – the debate continues Parkinson’s disease and dairy products Maternal seafood consumption and child development GM maize 1507 tested in 90-day rat feeding study Bad timing for the BBQ season – a new cooked beef mutagen is identified
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