PART I: WORLD NEWSINTERNATIONALIARC verdicts on 1,3-butadiene, ethylene oxide and three vinyl halides Draft SIDS Initial Assessment Reports (SIARs) OECD considers nanomaterials UN revises Globally Harmonized System of Classification and Labelling of Chemicals OECD workshop on perfluorocarboxylic acids and precursors OECD reports on in vitro testing of endocrine disruptors and uterotrophic bioassay
EUROPEAN UNIONKeep new guidance documents in REACH SCENIHR assessments on the health effects of smokeless tobacco products ... ... and on methods required to evaluate the risk of nanoparticles SCCP deliberations ... ... on phthalates in perfumes ... on HC Yellow No. 10 ... on 1,3-bis-(2,4-diaminophenoxy)propane ... and on 2-hydroxyethyl picramic acid, 4-nitrophenyl aminoethylurea and HC Red No. 13 EFSA’s latest pesticide assessments Draft assessment reports on five pesticides available from EFSA Food-contact materials – more EFSA assessments EFSA approves zeolite as a feed additive for dairy cows Hormone residues in meat assessed by EFSA EFSA evaluates ethyl lauroyl arginate Genetically modified (GM) soybeans assessed by EFSA EFSA guidance on health claim applications made on foods Report issued by EFSA on risk-benefit analysis of foods UNITED KINGDOMNasopharyngeal cancer and exposure to wood dust – IIAC opinion issued COMEAP draft report on air pollution and mortality COT statement on PAVA in stunning reformulated product Kiwiberry concentrate – ACNFP considers novel food application
UNITED STATESIRIS summary and supporting toxicological review for 2,2,4-trimethylpentane finalised Dimethylaminopropyl chloride, hydrochloride put through its NTP paces NTP RoC – draft background documents for captafol and ortho-nitrotoluene SAB reviews EPA assessments of arsenic’s carcinogenicity Updated and revised submissions to the EPA HPV Program OEHHA child specific reference doses for atrazine and deltamethrin Nanotechnology recommendations and regulatory implications – FDA talk tiny Pesticide tolerance petitions filed with the EPA Several pesticide tolerance announcements issued by the EPA EPA RED for benzoic acid, and related risk assessments on acrolein, bromonitrostyrene and naphthenate salts EPA pesticide Registration Review for fenoxycarb and urea sulphate FDA GRAS status for ammonium phosphatide EPA Exposure Factors Handbook for the more mature OTHER AUTHORITATIVE BODIESFSANZ safety assessments DECOS issues draft reviews on the carcinogenicity and genotoxicity of various chemicals RIVM scientists evaluate two-generation animal studies
PART II: SHORT CUTSDevelopmental toxicity of N-ethyl-2-pyrrolidone Arsenic workshop sponsored by US EPA Asbestos and lung cancer Diesel vegetable oil fuels genotoxic debate Diphenyl diselenide caused DNA damage in multiple organs in mice Reproductive and developmental toxicity of alkyl polyglucosides tested in rats Triclosan affected thyroid hormone levels in rats Limonene oxidation products may be more irritating to older lungs Brain tumours – a consequence of protecting a fine French wine? In utero exposure to anti-androgens adds up to changes in male sexual development Water disinfectant by-product reduces reproductive prowess of rabbits Ochratoxin A (OTA) and kidney carcinogenicity – a threshold mechanism may be involved Glucan from bakers yeast tested in 90-day study Sticky problems encountered with oligoglucosamine Milk tripeptides evaluated for safety-in-use Geniposide in gardenia yellow tested in 90-day rat feeding study Magnesium may help reduce the risk of diabetes Folate fortification and colorectal cancer Genistein tested in developmental study Different flavonoids may protect against oral and pharyngeal cancer Hydroquinone inhibits early stages of liver tumour formation in rats Toona sinensis Roemor leaves – freeze-dried water extract tested for toxicity Safety tests on Hopsphenon®, a polyphenol-rich hop bract extract Peppers may protect against breast cancer Grapefruit may leave sour taste for post-menopausal women Up the apples and pears to prevent lung cancer? Stop blinking … have a coffee break ... ... and how about another coffee for the liver? Sugar-sweetened drinks may not be linked to growth of obesity Red meat and endometrial cancer |