INTERNATIONALFindings released from JECFA’s 74th meeting Background document on uranium for WHO drinking water guidelines Endocrine disruptors – OECD issues draft review of new test methods OECD (Q)SAR Application Toolbox Version 2.2 now available EUROPEAN UNIONREACH – is the heat on? ...ECHA updates its registered substances database …Proposals for harmonised classification and labelling …Other REACH items of interest EFSA publishes draft assessment report on sedaxane Conclusion on prochloraz from EFSA More SCOEL toxicity reviews released SCCS issues opinions on ingredients in consumer products Flame retardant safety evaluated by EC Dietary HBCDDs assessed by EFSA Materials in contact with food – EFSA considers two further chemicals Flavouring group evaluations from EFSA EFSA tastes a barbeque summer Liquorice extract – all sorts of toxicity data evaluated by EFSA Genetically modified soybeans on EFSA’s menu EFSA releases draft guidance on subchronic toxicity testing for whole food/feed Default assumptions on risk assessment – draft EFSA guidance Draft EFSA opinion on TTC concept for predicting human health risks SCCS, SCHER and SCENIHR assess toxicity of mixed up chemicals Science beneath the surface of EFSA’s skin absorption guidance IVTIP considers toxicity testing in 21st century ECVAM evaluates human embryonic stem cells for in vitro toxicity testing JRC reviews in chemico approach to toxicity prediction UNITED KINGDOMCOC Statement on ‘para-occupational’ pesticide exposure and cancer New studies examined by COC on waste incinerators and cancer incidence Fumagillin genotoxicity – COM Statement update Alcohol and cancer burden on COC agenda ACNFP initial opinions on rooster comb extract… …phosphated distarch phosphate …and taxifolin Parliamentary report on peer-review of scientific publications FSA considers framework for non peer-reviewed data UNITED STATESIRIS toxicological review on urea finalised by EPA – a story of inadequate data Carcinogenicity of fluoride and TDCPP considered by OEHHA OEHHA PHG for hexavalent chromium CIR final and tentative reports and Scientific Literature Reviews on cosmetic ingredients FDA GRAS status – more food additives ICCVAM reviews mouse local lymph node assay (LLNA) ToxCast evaluated for reproductive toxicity prediction REST OF THE WORLDDECOS HBROEL for grain dust Dutch Health Council issues draft reports on carcinogenicity and genotoxicity Cancer risk of nitrosamines assessed by INSPQ Health Canada plumbs lead’s toxicological profile Something nasty in the water? Perchlorate evaluated by ANSES Acrylate ink component assessed by NICNAS APVMA considers safety of bispyribac sodium up to par …evaluates azinphos-methyl for fruit and nut cases …and assesses diuron Threshold of Toxicological Concern (TTC) for prenatal development |