A new (2008) bibra Toxicity Profile on benzyl butyrate is now available, the summary of which is provided below. Toxicity Profiles are comprehensive, yet concise, monographs on the hazard potential of individual chemicals. They are written by scientists specially trained in the evaluation of toxicity data and are prepared principally from primary information sources.

Benzyl butyrate did not induce skin sensitization in humans when tested as a dilute solution. The neat material evidently caused skin irritation in one individual, but was not irritating when applied to the skin of rabbits. In acute studies in laboratory animals, benzyl butyrate was of low oral and dermal toxicity, although central nervous system effects were noted in rats following oral exposure. According to citations, there was no obvious toxicity in limited studies involving repeated oral administration to rats. {179294}

The above item is taken from the November 2008 issue of Toxicology and Regulatory News which is sent automatically to members of bibra (click here for more details).

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