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Suitability of the TTC approach – exclusions, “special cases” and the “Cohorts of Concern”

Suitability of the TTC approach – exclusions, “special cases” and the “Cohorts of Concern”

It has been a while, but if you recall in the previous (and first) blog in this series, we gave the potted history of the main TTC benchmarks that can used to assess an untested chemical. For any exuding a structural suspicion of genotoxicity, the…

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The Threshold of Toxicological Concern (TTC) approach to risk assessment: “Origins”

The Threshold of Toxicological Concern (TTC) approach to risk assessment: “Origins”

A wide spectrum of risk assessors are enamoured of the TTC, which essentially uses a knowledge of the toxicological properties of the universe of tested chemicals to make conservative predictions of the likely toxicity of untested materials. It gives them pragmatic respite from the onward…

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