An ECETOC technical report discusses the human health risk assessment of substances in contact with the skin. Three linked decision tree approaches are recommended for:

  • deriving a health-based reference value
  • characterising initial risk
  • refining risk characterisation

Guidance is given on how to fill any identified data gaps, and options for the refinement of exposure assessment are presented.

European Centre for Ecotoxicology and Toxicology of Chemicals. Evaluation of systemic health effects following dermal exposure to chemicals. Technical Report No. 119. March 2013.,cntnt01,details,0&cntnt01by_category=22&cntnt01order_by=date%20Desc&cntnt01template=display_list_v2&cntnt01display_template=display_details_v2&cntnt01document_id=7081&cntnt01returnid=59


The above item was taken from the May 2013 issue of Toxicology and Regulatory News which is sent automatically to members of bibra (click here for more details).

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