EFSA has issued its opinion on the health risks of BPA in the diet, dust, cosmetics and thermal paper. A detailed toxicological assessment was carried out and a temporary tolerable daily intake (t-TDI) of 4 μg/kg bw/day was derived from a benchmark dose analysis of kidney effects seen in a two-generation study in mice. Additional uncertainties over mammary gland, reproductive, neurobehavioural, immune and metabolic system effects were considered in calculating this value. Current exposure estimates in the human population do not indicate that BPA represents a human health concern, but there was “considerable uncertainty” associated with estimated intakes from non-dietary sources.

European Food Safety Authority. Panel on Food Contact Materials, Enzymes, Flavourings and Processing Aids (CEF). Scientific opinion on the risks to public health related to the presence of bisphenol A (BPA) in foodstuffs. EFSA Journal 2015, 13(1), 3978. http://www.efsa.europa.eu/en/efsajournal/pub/3978.htm


The above items were taken from the March 2015 issue of Toxicology and Regulatory News which is sent automatically to members of bibra (click here)


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