EFSA has derived adequate intakes (AIs, the average observed intake by an apparently healthy population that is assumed to be adequate) for copper based on mean observed intakes in healthy populations. For adults, AIs of 1.6 and 1.3 mg/day are proposed for men and women, respectively. For children, AI values range from 0.4 mg/day (infants aged 7-11 months) to 1.3 mg/day (boys aged 10-17 years). For pregnant and breastfeeding women, EFSA derived an AI of 1.5 mg/day.

On the other hand, DRVs for iron were derived using a factorial approach involving measurements in iron turnover and iron losses from the body. For men and post-menopausal women, the population reference intake (PRI, the level of intake that is adequate for virtually all people in a population group) is 11 mg/day; whereas for pre-menopausal women EFSA set a PRI of 16 mg/day. PRIs for infants and children were estimated to range from 7 mg/day (for children aged 1‑6 years) to 13 mg/day (for girls aged 12-17 years).

European Food Safety Authority (2015). Panel on Dietetic Products, Nutrition and Allergies (NDA).

Scientific opinion on dietary reference values for copper. EFSA Journal 2015, 13(10), 4253, 51 pp. http://www.efsa.europa.eu/sites/default/files/scientific_output/files/main_documents/4253.pdf

Scientific opinion on dietary reference values for iron. EFSA Journal 2015, 13(10), 4254, 115 pp. http://www.efsa.europa.eu/sites/default/files/scientific_output/files/main_documents/4254.pdf


The above items were taken from the December 2015 issue of Toxicology and Regulatory News which is sent automatically to members of bibra (click here)

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