This genotoxicity test is used to assess the DNA-damaging potential of chemicals in various organs and tissues of exposed animals. EFSA has provided guidance on the minimum requirements for conducting and reporting such assays to ensure consistency in the acceptability and interpretation of test results until an OECD guideline becomes available.

European Food Safety Authority. Minimum criteria for the acceptance of in vivo alkaline comet assay reports. EFSA Journal 2012, 10(11): 2977.

http://www.efsa.europa.eu/en/efsajournal/doc/2977.pdf

The above item was taken from the January–February 2013 issue of Toxicology and Regulatory News which is sent automatically to members of bibra (click here for more details).