A report commissioned by EC’s Directorate-General for the Environment reviews the state of the science on the assessment of endocrine disrupters. A decision tree approach is proposed, based on the work of various Member States, and organisations including the European Centre for Ecotoxicology and Toxicology of Chemicals (ECETOC). Other recommendations include the creation of a separate regulatory class for endocrine disrupters, consideration of potency in a weight-of-evidence approach (together with other criteria such as lead toxicity, specificity, severity and irreversibility), and the further development of guidance for the interpretation of test data.

Kortenkamp A et al. (2011). State of the art assessment on endocrine disrupters. Final report. 23 December 2011. Project Contract Number 070307/2009/550687/SER/D3.

http://ec.europa.eu/environment/endocrine/documents/studies_en.htm (with annexes 1 to 3)


The above item was taken from the April 2012 issue of Toxicology and Regulatory News which is sent automatically to members of bibra (click here for more details).

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