As part of its mandate to produce toxicological profiles for substances on the National Priorities List, the ATSDR has recently released the finalised reports on silica and thorium. These profiles provide a thorough review of the toxicological and epidemiological data for each substance and an evaluation of the risks to human health from different routes of exposure. Also developed in this process are Minimal Risk Levels (MRLs), defined as an estimate of daily human exposure to a substance that is likely to be without an appreciable risk of adverse non-cancer health effects over a specified duration.

US Agency for Toxic Substances and Disease Registry (2019). Toxicological Profiles for silica (https://www.atsdr.cdc.gov/ToxProfiles/tp211.pdf) and thorium (https://www.atsdr.cdc.gov/ToxProfiles/tp147.pdf). September 2019.

 

The above items were taken from the November 2019 issue of Toxicology and Regulatory News which is sent automatically to members of bibra.

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