A recently published paper summarises the findings of a (2007) workshop at which a group of international experts discussed the various approaches used in the risk assessment of allergenic foods. Three main strategies were identified, safety assessments using thresholds (NOAEL/LOAEL) and uncertainty factors, safety assessments using benchmark dose techniques and margins of exposure, and risk assessments using probabilistic models. The workshop concluded that all three methodologies should continue to be considered as they all had different merits, but that “for all approaches, further improvement of input data is desirable” (Madsen C.B. et al., Food and Chemical Toxicology 2009, 47, 480; http://dx.doi.org/10.1016/j.fct.2008.12.001). {180870}

The above item was taken from the March 2009 issue of Toxicology and Regulatory News which is sent automatically to members of bibra (click here for more details).

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