Four new listings are included in the latest RoC, which contains a total of 243 substance profiles on agents that may potentially pose a human cancer hazard. Each monograph reviews the evidence for carcinogenicity (from human and animal studies), and provides supporting data on the possible carcinogenic mechanisms involved.

Among the new listings, o-toluidine is classified as “known to be a human carcinogen” on the basis of epidemiological studies linking exposure to bladder cancer. The other three compounds (1-bromopropane, cumene and pentachlorophenol) are each “reasonably anticipated to be a human carcinogen”.

US National Toxicology Program. Report on carcinogens, thirteenth edition. October 2014. http://ntp.niehs.nih.gov/pubhealth/roc/roc13/index.html

 

The above items were taken from the November 2014 issue of Toxicology and Regulatory News which is sent automatically to members of bibra (click here)

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