Four new listings are included in the latest RoC, which contains a total of 243 substance profiles on agents that may potentially pose a human cancer hazard. Each monograph reviews the evidence for carcinogenicity (from human and animal studies), and provides supporting data on the possible carcinogenic mechanisms involved.

Among the new listings, o-toluidine is classified as “known to be a human carcinogen” on the basis of epidemiological studies linking exposure to bladder cancer. The other three compounds (1-bromopropane, cumene and pentachlorophenol) are each “reasonably anticipated to be a human carcinogen”.

US National Toxicology Program. Report on carcinogens, thirteenth edition. October 2014.


The above items were taken from the November 2014 issue of Toxicology and Regulatory News which is sent automatically to members of bibra (click here)

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