A recent Supplement to the British Journal of Cancer presents a series of papers on “The Fraction of Cancer Attributable to Lifestyle and Environmental Factors in the UK in 2010”. They include cancers attributable to tobacco, alcohol, four dietary factors (meat, fruit and vegetables, fibre, and salt), overweight/obesity, inadequate physical exercise, exposure to hormones, infection, ionising or solar radiation, occupation, and reproductive factors.

Exposure to non-optimal levels of these 14 factors accounted for around 40-45% of cancers in the UK in 2010, amounting to about 134,000 cases, with tobacco smoking the biggest cause, followed by dietary factors, alcohol drinking and excess body weight. Occupational exposures accounted for over 11,000 cancer cases (3.7% of the total), in particular lung cancers (attributed to asbestos, silica, diesel engine exhausts and mineral oils), mesotheliomas (asbestos) and breast cancer (related to circadian disruption from shift work).

Parkin DM et al. (2011). British Journal of Cancer 105, Si-S81. The fraction of cancer attributable to lifestyle and environmental factors in the UK in 2010.

http://www.nature.com/bjc/journal/v105/n2s/index.html?WT.ec_id=MARKETING&WT.mc_id=BJ1202CK010 (full journal issue)


The above item was taken from the April 2012 issue of Toxicology and Regulatory News which is sent automatically to members of bibra (click here for more details).

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