Following its 130th meeting in March 2014, the CIR Expert Panel has made available four final (or amended final) safety assessments covering a large number of cosmetic ingredients. These assessments summarise the available data and possible human health effects for each compound as used in cosmetic products. The following chemicals, and groups of chemicals, are covered:

  • alkyl betaines
  • monosaccharides, disaccharides and related ingredients
  • pentaerythrityl tetra-di-t-butyl hydroxyhydrocinnamate
  • tocopherols and tocotrienols

In addition, the meeting also saw the approval of ten tentative safety assessments.

All of the ingredients reviewed at this meeting have been determined to be safe in the current uses, concentrations and conditions as described in the CIR reports.

The Panel has also made available five scientific literature reviews on:

  • alkyl phosphates
  • 2-amino-3-hydroxypyridine
  • Avena sativa (oat)-derived ingredients
  • ceramides
  • styrene and vinyl-type styrene copolymers

Cosmetic Ingredient Review Expert Panel.

Findings of 130th meeting held on 17-18 March 2014.

CIR reports (including scientific literature reviews) are searchable via

The above items were taken from the May 2014 issue of Toxicology and Regulatory News which is sent automatically to members of bibra (click here)

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