Toxicity Profile for Lactic acid (1990)
Abstract
Lactic acid is a normal constituent of the body and of certain foods. Its toxicity is largely related to its acidity, the pH of concentrated solutions being less than 1. Lactic acid has caused eye damage in a number of species and skin irritation in rabbits. Ingestion of lactic acid (or its calcium salt) by man has resulted in gastro-intestinal damage, and kidney injury has also been seen in infants. The acid was of low acute oral toxicity in laboratory animals, and damaged the kidneys, stomach and lungs of rabbits. No evidence of mutagenicity was seen in Ames bacterial tests although other genotoxicity screening assays were inconclusive.
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