Lithol rubine BK (1993)
Abstract
Lithol rubine BK produced little irritation when tested, as the diluted material, on the skin of man and rabbits, and failed to induce skin sensitization in man. It was of low acute oral toxicity to rats and caused kidney damage on repeated oral administration. Studies involving multiple oral doses to pregnant rabbits and rats showed no adverse foetal effects. Fertility was decreased in the second generation of a limited three-generation oral rat study but no other reproductive effects were reported. There was no evidence of carcinogenicity in a limited dermal study in mice. No mutagenic activity was detected in Ames bacterial tests using pure samples.
Toxicity Profiles are comprehensive, yet concise, monographs on the hazard potential of individual chemicals. They are written by scientists specially trained in the evaluation of toxicity data and are prepared principally from primary information sources. To see the full list of nearly 500 Toxicity Profiles currently available, please click here. Profiles can be obtained by contacting our help desk (e-mail document@bibratoxadvice.co.uk) or by completing the enquiry form on the Contact Us page.
Copyright © 1993 BIBRA Information Services Ltd