Toxicity Profile for 2,4,6-Tribromophenol (1991)
Abstract
2,4,6-Tribromophenol (TBP) was slightly irritant to rabbit skin and the mucous membranes of rats. It was of fairly low acute oral toxicity in rats. The sodium salt produced tremors and convulsions in rats given lethal oral doses, and damaged the lungs and gastro-intestinal tract. Rats repeatedly inhaling TBP dust became less active and developed liver and kidney damage, and urinary changes suggesting possible kidney damage were also seen after repeated application of TBP to rabbit skin. Oral administration to pregnant rats resulted in foetotoxic effects at a maternally toxic dose. It was not mutagenic in an Ames bacterial test.
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