Linalool (1995)
Abstract
Linalool was irritant to the skin of various species of laboratory animal. In man, it has shown some ability to cause skin irritation and sensitization. It was of low acute toxicity by the oral route in rats and when applied to the skin of rabbits. Effects on the liver and its associated enzymes have been observed in rats given repeated oral doses. Linalool was not mutagenic in Ames bacterial tests but has demonstrated some activity in a test for DNA damage and in mammalian cells in culture.
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