Toxicity Profile for Triethanolamine (1990)

Abstract

Triethanolamine (TEA) was an irritant to the skin and eyes of laboratory animals and man, and a skin sensitizer in man. It was of low acute oral and dermal toxicity to laboratory animals. On oral and dermal administration to rodents, the main target organs were the kidneys, liver and nerves. TEA has given some indication of carcinogenic activity in a feeding study in mice, but the evidence was inconclusive in rats receiving it in the drinking water. In general, TEA showed no genotoxicity in bacterial tests (including Ames mutagenicity assays) or in tests on mammalian cells in culture.

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