We have a simple aspiration

Our toxicology consulting services provide the highest standard of chemical hazard and risk assessment across the broadest range of industries and organisations. We aim to help our clients cope with the complex and ever-changing regulations framed to protect human health, and we endeavour to do this in a way that meets their time and budgetary constraints.

Our expertise

Hazard Characterisation

Our hazard assessments, generally based on in-depth searches of the scientific literature, aim to define the dose-response for all routes of each of a chemical’s toxicological propensities.

Risk Assessment

Our health risk assessments convert the toxicological hazard profile to a health-based guidance value, and compare this reference point to an estimate of human exposure.

Literature Searching & Monitoring Services

Robust risk assessments rely upon quality data. We are experienced searchers of major toxicity databases, giving us valuable access to Expert Group and primary reports.

Industries we work in

Our toxicology consultants have extensive experience, enabling
us to help our clients across various industries and sectors

Extractables + Leachables

We provide valuable support to the pharmaceutical, medical device and processing equipment industries by producing screening reports and, if warranted, full risk assessment reports relating to extractables and leachables (E&L).

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Medical Devices

We are adept at conducting biocompatibility assessments and biological safety evaluations of medical devices in compliance with ISO 10993, FDA and European guidelines, to help bring your device to market.

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Nicotine Products

We provide valuable advice on toxicological issues relating to e-cigarettes (and other nicotine delivery devices), and can support your regulatory submissions within the scope of EU TPD, UK TRPR and the US FDA PMTA.

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Food + Food Contact

Over many years our scientists have been providing independent assessments of the risks of chemical contamination of food and drink.

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At bibra we understand the importance of industry-specific knowledge – when people ask us what we do and how we can help them, we reply that we have one area of core expertise – toxicology – that we stick to, and do, exceptionally well.

Check out our latest blogs and case studies

Evaluation of the safety of two complex cosmetics ingredients

Case study

The client was interested in extending the conditions of use of two of its manufactured surfactants to cosmetics and requested a risk assessment in order to evaluate their safety in a range of rinse-off and leave-on products. The two surfactants are each a mixture of several different structurally-related chemicals.

Updating REACH dossiers following ECHA Evaluation decisions

Case study

Manufacturers of chemicals in, or importers into, the European Union are required under the REACH regulation to submit a dossier of information on their substances to the European Chemicals Agency (ECHA). The Agency can, after evaluating the information provided by the registrant, require the company to update or amend their dossier, including with the addition of new experimental data. This is called a “Compliance Check decision”

Cannabinoids – preparation of several inhalation focused toxicity profiles

Case study

The client requested the production of a series of urgent toxicity profiles for more than a dozen different cannabinoids, to support and inform their Research & Development (R&D) of new inhalable (non nicotine) consumer products (including their possible incorporation as ingredients into e liquids).

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