Since its inception in December 2000, the Protein Allergenicity Technical Committee of the International Life Sciences Institute has organised a series of workshops covering areas of deficiency in the assessment of protein allergenicity for the safety evaluation of genetically-modified crops. A recently published report that summarises these meetings (describing the state‑of-the-science and identifying future research needs) covers topics such as protein stability, bioinformatics, serum banks, animal models, food processing and harmonisation of testing. It is concluded that “no single factor has yet to be recognized as predicting food allergy in humans and, therefore, a weight-of-evidence approach…remains the best…for allergy assessment of novel proteins in food or feed”. This approach has been deemed successful, with “no reported cases of human allergic responses to any approved agriculture biotechnology product” (Thomas K. et al., Food and Chemical Toxicology 2009, 47, 1041; {181993}

The above item was taken from the July 2009 issue of Toxicology and Regulatory News which is sent automatically to members of bibra (click here for more details).

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