Food additive E 171 is a mixture of titanium dioxide particles of various sizes. The proportion of nanoparticles is highly variable (6-55% by number; up to 3.2% by mass), and there is debate concerning whether E 171 should be classified as a nanomaterial. ANSES has recently released a review of the toxicology data relevant to E 171, with a focus on studies published since its previous opinion on E 171 in 2017. Among its recommendations for future work were an extended one-generation reproductive toxicity study (EOGRTS), and further work to confirm or refute a tumour-promoting potential for the food additive.

French Agency for Food, Environmental and Occupational Health & Safety (ANSES) (2019). Opinion of the French Agency for Food, Environmental and Occupational Health & Safety on the risks associated with ingestion of the food additive E 171. ANSES Opinion Request No 2019-SA-0036. https://www.anses.fr/en/system/files/ERCA2019SA0036EN.pdf

 

The above items were taken from the August 2019 issue of Toxicology and Regulatory News which is sent automatically to members of bibra.

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