The Australian Pesticides and Veterinary Medicines Authority (APVMA) has released a technical document on the herbicide, 2,4-dichlorophenoxyacetic acid (2,4-D), which is now open for public consultation. This comprehensive report includes detailed information regarding the human and environmental toxicology of both the active constituent and the applied product, and covers aspects of occupational exposure. A new acceptable daily intake (ADI) for 2,4-D of 0.05 mg/kg bw was established, based on the results of two chronic toxicity studies in rats. The acute oral reference dose (ARfD) was set at 0.7 mg/kg bw, on the basis of neurotoxicological effects in rats.

Australian Pesticides and Veterinary Medicines Authority (2019). 2,4-D (2,4-dichlorophenoxyacetic acid). Review technical report. October 2019.


The above items were taken from the December 2019 issue of Toxicology and Regulatory News which is sent automatically to members of bibra.

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