A workshop hosted by ILSI (the International Life Sciences Institute) in 2007 brought together over 40 experts from government, academia and industry to discuss how novel proteins should be assessed for potential allergenicity. Discussions covered (bioinformatic) approaches for comparing novel proteins to known allergens, the role of proteomics in the allergen assessment process, in vitro methods (basophil activation assays) for evaluating allergic potential, and animal models for predicting allergenicity in humans (Thomas K. et al., Food and Chemical Toxicology 2008, 46, 3219). {178664}

The above item was taken from the October 2008 issue of Toxicology and Regulatory News which is sent automatically to members of bibra (click here for more details).

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